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Research Associate II, Process Development

Company: Bevov
Location: Santa Clara
Posted on: October 13, 2021

Job Description:

Job Description

The client mission is to create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable. They are passionate about designing gene circuits to improve the “intelligence” of cell and gene therapies in order to enhance their therapeutic effectiveness against a broad range of diseases that conventional medicines are unable to address.

 

The client find purpose and meaning knowing that their efforts have the potential to improve the lives of patients and their families with more effective and safer treatment options. With science as our foundation and empathy as their key guiding principle, colleagues become friends, managers become mentors, and with time, cancer becomes history.

 



They are seeking an enthusiastic, self-driven Research Associate to join its Process Science team that is focused on advancing new products and enabling technologies. This role will be part of a team of associates and scientists that develop processes and technologies for manufacturing NK-cell therapies. The position will require experimental design, experimental execution, troubleshooting and optimization of processes, data analysis, drafting of and presentation of results.

Responsibilities

  • Contribute to process development for cell therapy development programs, including natural killer (NK cells) and other therapeutic cell modalities.
  • Perform small- and large-scale experiments using primary cells to support multiple operations including expansion, gene editing, selection/expansion of clones, cell harvest, and cryopreservation.
  • Perform transductions on primary human cells via viral vectors and other genes delivery methods.
  • Supports process optimization efforts to increase process robustness, improve transduction efficiency, cell yield and purity.
  • Contribute to donor screening and testing processes using high-throughput assays.
  • Collaborate with research teams on relevant ex-vivo assays (Flow Cytometry, ELISA, Luminex-based assays and PCR).
  • Helps design and execute experiments with great attention to detail.
  • Maintain accurate lab records and notebooks.
  • Author protocols, reports, and standard operating procedure documents.
  • Present results in team meetings and delivers presentations to both small and large groups

Qualifications

  • Bachelor’s or Master’s degree in Cell & Molecular Biology or related life science field, with a minimum of 2 years of experience, preferably in a process development setting
  • Experience with mammalian tissue culture including both adherent and suspension cells.
  • Proficiency with flow cytometry strongly preferred.
  • Ability to design and execute experiments with minimal technical supervision.
  • Ability to multitask and meet deadlines in a fast-paced environment.
  • Highly organized and detailed oriented individual with strong troubleshooting and problem-solving skills.
  • Must be a team player, proactive, and willing to work in a small team environment.
  • Must have excellent verbal and written communication skills.
  • Proficient with MS Office and other commonly used software and technology platforms.
  • Self-motivated and eager to take on temporary responsibilities outside of the initial job description

Benefits

The client is a leading gene circuit company designing gene circuits to create a new generation of “smarter medicines" and enhance the therapeutic effectiveness of cell and gene therapies against a broad range of diseases that are unaddressed by current standards of care. We are proud to count Leaps by Bayer, NEA, 8VC, Matrix Partners China, Mirae Asset Capital, Amgen Ventures, Intel Capital, Ridgeback Capital, Lux Capital, KB Investment, Pear VC, Smilegate Investment, Menlo Ventures, LifeSci Venture Partners, Alexandria Venture Investments, Allen & The company, LifeForce Capital, Omega Funds, Nest.Bio, Gaingels, Noveus Capital, and Goodman Capital among our investors and company is based in South San Francisco, CA, USA.

Base pay and stock options are to be determined based on applicant qualifications with the aim of being competitive with similar roles in the area.
Significant growth opportunity as the company expands 

Keywords: Bevov, Santa Clara , Research Associate II, Process Development, Other , Santa Clara, California

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