Associate Director, Biostatistics
Company: Alumis Inc.
Location: South San Francisco
Posted on: December 31, 2025
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Job Description:
Alumis Inc. is a precision medicines company with the mission to
transform the lives of patients with autoimmune diseases. Even with
treatment innovations of the last two decades, many patients with
immunologic conditions continue to suffer - our goal is to
fundamentally change the outcomes for these patients. We are
seeking an Associate Director of Biostatistics to provide
statistical expertise and operational support across a variety of
clinical activities with a focus on supporting early-stage and
late-stage clinical programs. This role will serve as lead study
statistician, collaborating with cross-functional teams to support
clinical development and data-driven decision-making. The Associate
Director will contribute hands-on to key deliverables, manage CROs,
and provide guidance to junior team members. Essential
Responsibilities: Contribute to the statistical design and analysis
of early and late phase clinical studies. Apply advanced
statistical methods and data visualization skills to clinical trial
data summaries and interpretations such as integrated safety and
efficacy analyses for regulatory submissions. Serve as the
biostatistics representative on cross-functional teams, ensuring
alignment of statistical approaches with study and program
objectives. Provide input on study design, endpoint selection, and
sample size planning. Draft statistical analysis plans (SAPs) and
support interpretation of results. Ensure the quality and accuracy
of statistical deliverables by independently generating the
statistical deliverables and/or independently reviewing and
validating the statistical deliverables generated by either CRO or
internal statistical programming team. Manage CROs and mentor
junior staff or contractors as appropriate. The Ideal Candidate:
Education: Ph.D. in Biostatistics with 6 years of relevant industry
experience, or Master’s with 8 years. Experience: Significant
experience serving as a study statistician on global Phase III
clinical trials, ideally in immunology or immune-mediated diseases.
Demonstrated track record of supporting regulatory submissions
(NDA/BLA/MAA), including integrated safety/efficacy analyses.
Hands-on experience working in a biotechnology or pharmaceutical
company environment (not only CRO, Site, or Academic). Proven
ability to manage CROs and statistical programming teams in a
sponsor setting. Strong foundation in clinical trial design,
statistical analysis, and regulatory guidelines. Proficiency in
statistical programming (SAS and R). Experience in publication work
and/or analysis of real-world data preferred. Demonstrated ability
to manage multiple priorities and work cross-functionally.
Experience with both early-stage and late-phase clinical trials.
Skills: Strong analytical thinking and attention to detail.
Excellent verbal and written communication skills. Ability to work
independently in a fast-paced, regulated environment. Ability to
manage deliverables with competing priorities and influence others
effectively. Strong organizational skills, with the ability to
manage workflows and activities to meet department timelines.
Collaborative mindset and ability to influence without authority.
The salary range for this position is $190,000 USD to $230,000 USD
annually. This salary range is an estimate, and the actual salary
may vary based on the Company’s compensation practices. This
position is located in South San Francisco, CA, with an expectation
to be onsite Tuesday through Thursday. While we prefer local
candidates, remote applicants based in the Pacific Time Zone will
be considered on a case-by-case basis. Alumis Inc. is an equal
opportunity employer. Alumis compensation packages include generous
stock option grants for all employees as well as an annual bonus
program. Other benefits include: Health insurance premiums paid at
90% for employee, 80% for dependents Free access to Genentech Bus &
Ferry Share program $100 monthly cell phone stipend Unlimited PTO
for Exempt employees Free onsite gym and a kitchen stocked with
yummy snacks and drinks! We are a hard-working, collaborative team
on a mission to transform patient’s lives and we aspire to elevate
, challenge and nurture one another along the way.
Keywords: Alumis Inc., Santa Clara , Associate Director, Biostatistics, Science, Research & Development , South San Francisco, California
